AP Biology — Genetics & Heredity

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Define **allele**.

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Define **allele**.

An **allele** is a variant form of a gene. Different alleles can result in different traits.

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What is **homozygosity**?

Homozygosity occurs when an individual has two identical alleles for a particular gene.

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What does **heterozygous** mean?

An individual is **heterozygous** for a gene if they have two different alleles at a gene locus.

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Describe **dominant** allele.

A **dominant** allele is one that expresses its trait even when only one copy is present in a genotype.

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What is a **recessive** allele?

A **recessive** allele is one that only expresses its trait when two copies are present in a genotype.

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What is **codominance**?

**Codominance** occurs when both alleles in a heterozygote are fully expressed, resulting in a phenotype that displays both traits.

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Explain **incomplete dominance**.

**Incomplete dominance** is a genetic situation where the phenotype of the heterozygote is intermediate between the two homozygotes.

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Define **genotype**.

A **genotype** is the genetic makeup of an organism, represented by the alleles it possesses.

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Define **phenotype**.

A **phenotype** is the observable traits or characteristics of an organism, resulting from the interaction of its genotype with the environment.

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What is **Mendel's Law of Segregation**?

Mendel's Law of Segregation states that during the formation of gametes, the alleles for a trait separate, so each gamete carries only one allele for each trait.

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What is a **gene**?

A **gene** is a segment of DNA that contains the instructions for the synthesis of a specific protein or RNA molecule.

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Describe **Mendel's Law of Independent Assortment**.

Mendel's Law of Independent Assortment states that genes for different traits can segregate independently during the formation of gametes.

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What is a **Punnett Square** used for?

A **Punnett Square** is a diagram used to predict the genotypes and phenotypes of offspring from a genetic cross.

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What is **linkage** in genetics?

In genetics, **linkage** refers to the tendency of genes located close together on a chromosome to be inherited together.

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Define **genetic recombination**.

**Genetic recombination** is the process by which genetic material is rearranged during meiosis, resulting in new allele combinations.

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What is a **test cross**?

A **test cross** is a genetic cross between an individual with an unknown genotype and a homozygous recessive individual to determine the unknown genotype.

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What is **epistasis**?

**Epistasis** is an interaction between genes in which one gene masks or interferes with the expression of another.

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Define **pleiotropy**.

**Pleiotropy** occurs when one gene influences multiple phenotypic traits.

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What is **polygenic inheritance**?

**Polygenic inheritance** involves multiple genes contributing to a single phenotypic trait, often resulting in continuous variation.

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What is the **Hardy-Weinberg Principle**?

The **Hardy-Weinberg Principle** states that allele and genotype frequencies will remain constant in a population from generation to generation in the absence of evolutionary influences.

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State the Hardy-Weinberg equation.

The Hardy-Weinberg equation is $p^2 + 2pq + q^2 = 1$, where $p$ and $q$ represent the frequencies of the alleles.

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What is **genetic drift**?

**Genetic drift** is the change in the frequency of an allele in a population due to random sampling of organisms.

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Define **bottleneck effect**.

The **bottleneck effect** is a sharp reduction in the size of a population due to environmental events or human activities, leading to a loss of genetic diversity.

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What is the **founder effect**?

The **founder effect** occurs when a small group from a population establishes a new population with a different allele frequency than the original population.

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Describe **gene flow**.

**Gene flow** is the transfer of genetic material between separate populations, leading to changes in allele frequencies.

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What is **mutation**?

A **mutation** is a change in the DNA sequence that can lead to genetic diversity and potentially result in new traits.

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What is **natural selection**?

**Natural selection** is the process where organisms with favorable traits are more likely to survive and reproduce, leading to evolutionary changes.

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Define **sexual selection**.

**Sexual selection** is a form of natural selection where individuals with certain characteristics are more likely to attract mates and reproduce.

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What are **sex-linked traits**?

Traits that are determined by genes located on sex chromosomes, often resulting in different patterns of inheritance in males and females.

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Explain **X-inactivation**.

**X-inactivation** is the process by which one of the two X chromosomes in females is randomly inactivated, leading to dosage compensation.

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What is a **karyotype**?

A **karyotype** is a visual representation of an individual's chromosomes, arranged by size and shape.

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Define **genome**.

A **genome** is the complete set of genetic material present in an organism or cell.

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What is **genetic engineering**?

**Genetic engineering** is the manipulation of an organism's genome using biotechnology to create desired traits.

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Describe the process of **gene cloning**.

**Gene cloning** involves isolating a specific gene and making multiple copies of it, often using bacterial plasmids.

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What is **CRISPR-Cas9**?

**CRISPR-Cas9** is a genome editing tool that allows for precise modifications to DNA sequences in cells.

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What is the role of **RNA interference** (RNAi)?

**RNA interference** (RNAi) is a biological process where RNA molecules inhibit gene expression by neutralizing targeted mRNA molecules.

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Define **transgenic organism**.

A **transgenic organism** is an organism that has been genetically modified to contain DNA from a different species.

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