Human Anatomy — Muscular System

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Skeletal muscle

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All Terms (38)

Skeletal muscle

A type of muscle tissue that is attached to bones and enables voluntary movement

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Smooth muscle

Involuntary muscle tissue found in walls of internal organs and blood vessels

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Cardiac muscle

Involuntary muscle tissue found only in the heart

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Sarcomere

The basic contractile unit of muscle fiber

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Actin

A thin filament protein in muscle fibers that interacts with myosin for muscle contraction

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Myosin

A thick filament protein that interacts with actin for muscle contraction

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Neuromuscular junction

The synapse between a motor neuron and a skeletal muscle fiber

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Acetylcholine

Neurotransmitter released at the neuromuscular junction to stimulate muscle contraction

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Sliding filament theory

The process by which actin and myosin filaments slide over each other during muscle contraction

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Tendons

Connective tissues that attach muscles to bones

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Ligaments

Connective tissues that connect bones to other bones

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Motor unit

A single motor neuron and all the muscle fibers it innervates

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Muscle hypertrophy

An increase in muscle size due to an increase in the size of individual muscle fibers

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Muscle atrophy

A decrease in muscle mass due to disuse or denervation

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Isometric contraction

Muscle contraction without a change in muscle length

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Isotonic contraction

Muscle contraction with a change in muscle length

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Fast-twitch fibers

Muscle fibers that contract quickly and generate high force but fatigue rapidly

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Slow-twitch fibers

Muscle fibers that contract slowly and are resistant to fatigue

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Glycolysis

A metabolic pathway that converts glucose into pyruvate, providing energy for muscle contractions

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Creatine phosphate

A molecule that can quickly donate a phosphate to ADP to regenerate ATP in muscle cells

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What is the role of calcium in muscle contraction?

Calcium ions bind to troponin, causing a conformational change that moves tropomyosin away from actin's myosin-binding sites, allowing contraction.

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Troponin

A protein complex involved in muscle contraction that binds calcium ions

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Tropomyosin

A protein that blocks myosin-binding sites on actin molecules in resting muscle

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Rigor mortis

A postmortem condition where muscles become stiff due to the lack of ATP required to release myosin from actin

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ATP's role in muscle contraction

ATP binds to myosin, allowing it to detach from actin and re-cock for another power stroke

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Endomysium

Connective tissue surrounding individual muscle fibers

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Perimysium

Connective tissue surrounding a bundle of muscle fibers (fascicle)

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Epimysium

Connective tissue surrounding an entire muscle

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What is muscle fatigue?

The decline in ability of a muscle to generate force, often due to prolonged activity, lack of energy, or accumulation of metabolic byproducts.

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Myoglobin

An oxygen-binding protein in muscle cells that provides a reserve of oxygen for aerobic ATP production

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What is the function of the sarcoplasmic reticulum?

The sarcoplasmic reticulum stores calcium ions and releases them upon stimulation to initiate muscle contraction.

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Muscle spindle

A sensory receptor located in muscles that senses changes in muscle length

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Golgi tendon organ

A sensory receptor located at the junction of a muscle and its tendon, sensitive to changes in muscle tension

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Fascicle

A bundle of skeletal muscle fibers surrounded by perimysium

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What is the all-or-none principle in muscle contraction?

A muscle fiber will contract to its full potential when stimulated; there is no partial contraction.

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Origin of a muscle

The fixed attachment point of a muscle, typically proximal

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Insertion of a muscle

The movable attachment point of a muscle, typically distal

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What is the role of ATPase in muscle contraction?

ATPase is an enzyme on the myosin head that hydrolyzes ATP, providing energy for the power stroke during contraction.

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